Formulation and Evaluation of Herbal Screen Detox Eye and Brain Supplement Gummies

Author

Raushan Kumar, Mrs. Mahalakshmi S, Dr. Kavitha P N

Abstract

 Longer use of smartphones, computers, tablets , and other digital gadgets has been linked with digital eye strain and visual tiredness, headaches as well. People also report trouble staying on task and overall mental exhaustion, you know, that kinda thing. Nutraceutical formulations that include antioxidants from natural sources plus different bioactive compounds might give nutritional backup for eye related wellness and cognitive performance. Then there are gummy dosage forms, they act like a handy and more enjoyable swap compared to ordinary tablets or capsules, so administration often feels easier and people tend to accept them better.

This present study was made to formulate and check herbal eye and cognitive health-support gummies, using selected herbal ingredients alongside bioactive nutrients, vitamins, minerals, and natural pharmaceutical excipients. We also ran molecular docking and in-silico toxicity prediction to get early computational hints about biological interactions and possible safety angles for the picked bioactive constituents. The gummies were produced through a heat-and-pour approach, pectin was used as the main gelling agent, and gum acacia served as a stabilizing and binding agent, kinda together to keep things in place. The formula included Ginkgo biloba, blueberry, spinach, plus lutein, vitamins A, C and E and some selected seed powders. After making them, the gummies were examined for appearance, colour, aroma, taste, texture, weight variation, pH, hardness, moisture content, phytochemical profile, and stability.

The optimized gummies showed a uniform, smooth, glossy look, with a pleasant fruity aroma and a sweet fruity taste, nothing too complicated. Their texture was soft chewy, and non-sticky . The formulation had a pH of 3.6, weight variation stayed within the allowed ±5% limit, and moisture content was about 15%. During the stated stability assessment, no major changes showed up. Molecular docking results suggested favourable binding interactions between selected bioactive compounds and relevant target proteins, where lutein had a docking score of −11.2 kcal/mol against VEGFR2 among the compounds that had numerical values provided. The in-silico toxicity prediction overall suggested generally favourable preliminary safety profiles for several chosen constituents, even though a few predicted issues still need more experimental checking.

Overall, the herbal gummies that were developed gave satisfactory physicochemical and sensory results, plus early computational evidence that supports further exploration of the selected bioactive constituents. This formulation could be seen as a nutraceutical route for nutritional support related to eye and cognitive health, yes. But still, in-vitro work, clinical studies , and longer-term safety testing are required before anyone tries to state therapeutic or health related claims.

Keywords

Digital eye strain; Herbal gummies; Nutraceutical; Ginkgo biloba; Lutein; Blueberry; Spinach; Cognitive health; Eye health; Molecular docking; In-silico toxicity.Keywords: Digital eye strain;

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